Dr Milos Tanurdzic
My research interests are at the intersection of plant genomics, chromatin biology and epigenetics. The research effort in my group is focused on the cooperative roles of DNA methylation, histone modifications, and RNAi in establishment and maintenance of epigenetic states throughout plant genomes, both at repetitive DNA sequences as well as in gene promoters and other control regions. We are particularly interested in the roles these mechanisms play in creating and maintaining heritable epigenetic variation in natural populations, as well as in inheritance of epigenetic states in inter- and intra-specific crosses in plants, in order to understand how epigenetic mechanisms contribute to plant development, adaptation, natural selection and evolution.
Tanurdzic, M., Vaughn, M., Jiang, H., Lee, T-J., Slotkin, R., Sosinski, B., Thompson, W., Doerge R., and Martienssen, R.(2008) Epigenomic consequences of immortalized plant cell suspension culture. PLoS Biology 6(12): e302.
Vaughn, M.,* Tanurdzic, M.*, Lippman, Z.*, Jiang, H., Carrasquillo, R., Rabinowicz, P., Dedhia, N., McCombie, W.R., Agier, N., Bulski, A., Colot., Doerge, R. W., and Martienssen, R.A. (2007) Epigenetic Natural Variation in Arabidopsis thaliana. PLoS Biology 19;5(7): e174.
The Selaginella Sequencing Consortium. (2011) The Selaginella genome reveals insights into the origin and radiation of vascular plants. Science 332 (6032): 960-963.
Slotkin, R. K., Vaughn, M. W., Borges, F., Tanurdzic, M., Becker, J. D., Feijo, J. A., Martienssen, R.A. (2009) Epigenetic reprogramming and small RNA silencing of transposable elements in pollen. Cell 136(3): 461-72.
Tanurdzic, M. and Banks, J.A. (2004) Sex determining mechanisms in land plants. Plant Cell 16: S61-71.